The drug Nitromint: instructions for use in the form of a spray or aerosol

Instructions for use of the drug Nitromint

Nitromint is a vasodilator that comes in the form of a spray or aerosol for sublingual application. Substance - a colorless, transparent and without sediment liquid, packaged in aluminum or COS (cycloolefin copolymer) cylinders with a spray pump, which dose the medicine.

Nitromint is a peripheral vasodilator, which mainly affects the tone of the veins. Relaxing the smooth muscles of the vascular wall, reduces the load on the heart and reduces myocardial oxygen demand. In addition, the coronary vessels expand, blood circulation and the delivery of all necessary substances to the myocardium are improved.

In addition, nitroglycerin (active ingredient), suppressing pain, produces a central inhibitory effect on the sympathetic system and its effect on vascular tone. The effect starts after one and a half minutes and lasts about half an hour.

Indications for use: what is this remedy used for?

The main indication for the use of Nitromint is exertional angina. The drug is taken to relieve a painful attack or prevent it, for example, before starting physical activity.

Also, nitroglycerin is used in the treatment of left ventricular failure, as an adjunct to other drugs. Perhaps an appointment to lower the pressure during myocardial infarction. In addition, Nitromint is prescribed before coronary angiography of the coronary vessels to prevent spasms.

Method of administration and dosage of the drug

The drug bottle contains 10 mg of liquid, which contains 180 doses. One dose contains 0.4 mg of nitroglycerin. The spray or aerosol form is intended for sublingual use only.

After opening a new package, before the first use, it is necessary to first fill the dosing pump. To do this, press the valve several times until the aerosol appears.

When applying the medication, the balloon must be held upright, with the spray upwards, preferably in a sitting position. During use of the spray, it is necessary not to breathe, to prevent the aerosol from entering the respiratory tract. If you need to enter an additional dose, then it is better to do it after 30 seconds.

Instructions for the use of Nitromint spray:

• to relieve pain during angina pectoris, 0.4-0.8 mg of the drug is administered under the tongue, which is equal to 1-2 doses, if necessary, you can take another 1 dose. A maximum of 3 sprays are allowed in 15 minutes. If the pain is not relieved, an urgent need to consult a doctor, as myocardial infarction may develop;
• in order to prevent stenocarditis attack 5-10 minutes before physical activity, take 1 dose;
• during the treatment of acute left ventricular failure with the development of pulmonary edema, 1.6 mg (4 injections) of Nitromint is used for a short period of time, while the patient is under the supervision of a physician. If necessary, you can re-enter the same dose after 10 minutes;
• 1-2 doses are administered before coronary angiography.

For the treatment of Nitromint in elderly people, correction of the frequency and dosage of use is not required.

Spray

Spray Nitromint, as already mentioned, is packaged in vials made of DSP material with a capacity of 10 mg (180 doses). The peculiarity of this form of release is that the drug is applied using a mechanical piston pump, while the pressure in the container is the same as atmospheric. The spray atomizes particles ranging in size from 10 to 50 microns, which allows the active substance to be rapidly absorbed through the mucous membrane into the bloodstream and begin to act in a minute or two.

The convenience of this package is that you can always see how much preparation is left (since the glass is translucent).

Spray can

An aerosol, unlike a spray, is packaged in aluminum cylinders, and the liquid is under pressure. Due to this, the drug is sprayed in the form of smaller particles from 1 to 5 microns, which allows the drug to be absorbed even faster.

However, aerosol packaging requires some precautions. Since the cartridge is under pressure, there is a risk of fire. Store Nitromint in a place protected from direct sunlight at a temperature of 15-25. Do not spray near sources of fire or while smoking.

Otherwise, there are no differences from the aerosol form from the Nitromint spray. They have the same volume and composition. Also in one injection the same amount of active ingredient.

Contraindications and side effects

There are absolute and relative contraindications to the use of Nitromint.

Nitromint is strictly prohibited for use with:

• cardiogenic shock;
• the presence of vascular collapse;
• allergy to drug components or organic nitrates;
• children under 18.

In the presence of the following pathologies, Nitromint should be prescribed only by a doctor after assessing all the risks:

• frequent episodes of orthostatic hypotension (a sharp drop in pressure when changing body position);
• severe anemia;
• diseases of the thyroid gland, the presence of thyrotoxicosis;
• increased intracranial pressure;
• acute cardiovascular failure with severe hypotension (systolic pressure below 90 mm Hg);
• recent hemorrhagic stroke;
• migraine;
• hypertrophic cardiomyopathy;
• acute coronary syndrome accompanied by hypotension;
• disruption of the kidneys or liver;
• traumatic brain injury;
• alcohol addiction;
• angle-closure glaucoma
• during pregnancy and lactation, it is used if the expected benefit is higher than the possible risks.

The appearance of side effects is also possible:

1. The effect of the drug on the central nervous system is manifested in the form of complaints of general weakness, less often of disorientation in space, anxiety, lethargy, imbalance.
2. Frequent effects on the cardiovascular system: drop in blood pressure, headaches, rapid heartbeat, dizziness, feeling of heat. Rare: orthostatic hypotension, cyanosis.
3. The effect of the drug on the digestive system is the appearance of dry mouth, nausea and vomiting, and abdominal pain.
4. Allergic reactions in the form of skin rashes, itching.
5. Local reactions: redness of the neck and face, burning sensation under the tongue.

Analogues and substitutes for the remedy: what can you take instead?

Nitromint is a high-quality, fast-acting drug due to its form of release in the form of a spray or aerosol. But sometimes he is absent in the pharmacy. If there is an urgent need to purchase some nitroglycerins, you can pick up something from the analogs of Nitromint:

• Nitroglycerin - can be purchased as a tablet or aerosol (Nitroglycerin-Aerosol);
• Sustak - tablets with prolonged action (in 1 tablet - 6.4 mg of nitroglycerin);
• Nitrospray, Nitrospray-ICN, Nitrosprint - dosed sublingual sprays (1 dose-injection - 0.4 mg of nitroglycerin);
• Nitro-concentrate for intravenous infusion (in ampoules of 2 and 5 ml), is prescribed only by a doctor in a hospital setting.

Conclusions

Nitromint is a modern drug with vasodilating and antianginal effects. Due to their form of release, small particles are quickly absorbed and have an almost instant effect.

The drug is dispensed in a pharmacy without a prescription, but before starting treatment, you need to consult with your doctor and find out the cause of the pain in the heart area. Before using Nitromint, you must carefully read the instructions and adhere to all recommendations and warnings.