Cardiology

Funds and medicines for VSD: a list of drugs

List of drugs for the treatment of vascular dystonia

There are several different approaches to the treatment of any pathology, including VSD:

  1. Etiotropic therapy. It is aimed at eliminating the immediate cause of the disease (for example, antibiotics for pneumonia kill pathogenic bacteria, the toxic effect of the microorganism stops, lung tissue is restored - the patient recovers). The cause of angioedema is difficult to establish precisely, since the symptoms affect different organ systems, provoking completely opposite symptoms in a short period. In this regard, the etiotropic method is not used.
  2. Pathogenetic treatment. Here, the emphasis is on blocking the body's response to an internal or external agent (for example, the use of non-steroidal anti-inflammatory drugs to lower the temperature in a patient with pneumonia). With VSD, a similar therapy can be treatment aimed at:
    • decreased activity of electrical processes in neurons - sedatives;
    • additional stimulation of the peripheral nervous system - with asthenic syndrome;
    • correction of dysfunctions of peripheral organs - occurs in pathologies of the spinal cord and spine.
  3. Symptomatic treatment. A therapy of this nature removes only visible manifestations of deep processes (for example, pain relievers).

For the treatment of autonomic disorders, it is advisable to use a pathogenetic and symptomatic approach. The remedy for VSD is prescribed based on the clinical manifestations of the disease in each specific patient.

Most often, according to patient reviews, the following groups of drugs are used:

  • depressing activity of the nervous system:
    • sedatives (have a sedative effect);
    • tranquilizers (the effect of inhibition of consciousness is more pronounced than that of sedative pills);
    • antipsychotics (also called antipsychotics, since they are intended to correct severe mental disorders associated with aggression and panic);
    • sleeping pills (help to normalize the rhythm of sleep and wakefulness);
  • stimulating the activity of the brain and metabolic processes in the body:
    • nootropics (spur on the activity of areas of the hemispheres responsible for mental work);
    • antidepressants (affect the production of endogenous "pleasure mediators");
    • drugs with a general tonic effect (or adaptogens, increase the overall activity of metabolic and energy processes in the body);
  • dietary and dietary supplements:
    • vitamins (serve as catalysts for important biochemical processes, the result of which is the material and functional integrity of the body);
    • amino acids (prescribed in case of insufficient intake with food or metabolic disorders in the body);
    • mineral complexes (used to replenish the ion-electrolyte balance and the normal conduction of nervous excitation along the processes of neurons to peripheral organs);
  • tablets that prevent the destruction of body cells:
    • antioxidant agents (thanks to them, tissue areas with reduced blood supply suffer less);
  • hormonal drugs (especially important for the elimination of symptoms of vegetative-vascular dystonia, provoked by menopause in women);
  • homeopathic remedies (it is believed that they do an excellent job with psychogenic variants of the VVD, especially at the stage of the absence of structural changes in tissues, but at the same time have no effectiveness from the point of view of evidence-based medicine);
  • pills affecting the "suffering" more than the rest of the organ system:
    • cardiovascular group:
      • blood pressure lowering agents;
      • antihypertensive drugs;
      • antianginal (for cardiac pain);
      • vasodilating drugs.

Adult patients

In adulthood, symptoms of the disease usually worsen. There are fewer and fewer such situations when the signs are so weak that you can get by with drugs of general strengthening action. And the demands of adult patients are greater: you need to continue to perform work duties with the same level of stress, but the effect is expected by them as soon as possible. In the tables and lists presented below, there are the most used medicines for the treatment of angioedema with an indication of the group, the active substance and the characteristics of the action.

Drugs for the treatment of VSD, depressing brain activity

GroupRepresentativesMechanism of actionThe rendered effect
SedativesMeans based on valerian and lemon balm, dog nettle, motherwort, hawthorn fruits, coriander, hop cones. Magnesium compounds and bromides are usedNormalization of the activity of the autonomic part of the peripheral nervous systemRelieve excessive emotional stress, irritability, stabilize the state of mind
TranquilizersDiazepam, Nozepam, Elenium, Oxazepam, SeduxenSuppression of brain structures, the activity of which gives rise to pathological emotional reactionsAnxiolytic (remove anxiety) effect. Eliminate psychoses (inappropriate actions and perception of the world), phobias (groundless fears)
AntipsychoticsSulpiride, Chlorprothixene, LevomepromazineInfluence dopamine-dependent processes in the brainAntipsychotic (correction of the pathology of consciousness), sedative, to some extent hypotensive, antidepressant and antiemetic effects
Hypnotics"Donormil"Blocking histamine receptorsThey have a calming effect and induce deep sleep. Sedatives can also be used as sleeping pills, but then you need to increase the dose taken 3-10 times
"Zolpidem"Acts on benzodiazepine receptors
"Ramelteon"Activates melatonin receptors
"Suvoreksat"Stimulates orexin-sensitive areas
"Bromized"Reduces the activity of excitation processes in the cerebral cortex

Drugs that inhibit the nervous system should be taken only after consulting a doctor. Despite the seeming harmlessness of hypnotics and sedatives (most of the representatives of these groups are sold in pharmacies in the public domain), as well as their captivating "natural" composition, they can provoke a complication of the course of vegetative vascular dystonia.

Side effects that certain drugs from these groups exhibit:

  • sedatives:
    • slight decrease in performance;
    • slight dizziness;
    • dry mouth;
    • nausea;
    • disorder of the menstrual cycle;
    • weakening of the effect of contraceptives;
    • decreased effectiveness of anticoagulants (blood-thinning drugs);
  • sleeping pills:
    • daytime sleepiness;
    • heavy awakening;
    • rapid fatigue (especially with active mental work);
    • decrease in the speed and adequacy of the reaction;
    • "Recoil syndrome" - a disturbance in the rhythm of sleep after a sudden discontinuation of the drug;
    • the emergence of dependence on the medication used (very quickly a person becomes unable to fall asleep without a pill);
    • dizziness when exceeding the recommended doses;
    • memory gaps and loss of clarity of thought (especially in the elderly).

Medicines from the following two groups are prescribed only in extreme cases (with severe VSD, frequent and prolonged panic attacks):

  • tranquilizers:
    • muscle relaxation (a significant decrease in muscle tone throughout the body or in certain areas);
    • suppression of the manifestation of normal emotions;
    • dulling the sensitivity of receptors (when your favorite cake does not seem so tasty, and the pleasure remains in question);
    • paradoxical reactions (increased anxiety and excitability of the patient as a result of taking the drug);
  • antipsychotics:
    • drowsiness;
    • weight gain;
    • dry mouth;
    • constipation;
    • disorder of the nervous system (the appearance of tremors, impaired coordination of movements when walking and in a static position, obsessive subconscious movements of the limbs);
    • arrhythmias;
    • degenerative changes in the retina;
    • jaundice (due to stagnation of bile);
    • vegetative disorders.

Means that improve the functioning of the nervous system

GroupRepresentativesMechanism of actionThe rendered effect
Nootropics"Hopantenic acid", "Phenibut", "Piracetam"Influence the metabolism of gamma-aminobutyric acid (the main inhibitory mediator of the brain)Increasing the resistance of neurons to hypoxia and the action of toxic substances, stimulation of synthetic processes. Reducing motor excitement, improving work capacity
Antidepressants"Fluoxetine", "Venflaxin", "Imipramine", "Pirlindol", "Maprotiline"They inhibit the reuptake of serotonin (one of the "hormones of joy"), norepinephrine, dopamineAnxiolytic (reducing anxiety), antidepressant (restoring the ability to enjoy life), sedative

Side effects of stimulant medications to consider while taking:

  • nootropics (rarely occurring):
    • worsening insomnia;
    • provoking seizures (in patients with epilepsy);
    • "Robbery syndrome" (irrational redistribution of blood in the body, which causes oxygen starvation of important organs);
  • antidepressants:
    • nausea;
    • decreased appetite;
    • bowel dysfunction (constipation or diarrhea);
    • dry mouth;
    • libido disorders (until the complete loss of sexual desire);
    • sleepiness at an inopportune time of the day;
    • difficulty falling asleep;
    • irritability.

Dietary supplements and food complexes

GroupRepresentativesMechanism of actionThe rendered effect
Vitamins"Milgamma" (B1, B6, B12)Influences the metabolism of amino acids important for the nervous tissue. Improves impulse conduction in synapsesNormalizes the functioning of the brain, spinal cord and peripheral nerves
Amino acids"Eltacin" (contains glycine, L-glutamate, L-cystine)An inhibitory neurotransmitter that provides the building blocks for building proteins the body needsEliminates psycho-emotional stress. Improves metabolism and prevents hypoxic changes in tissues. Stimulates regeneration processes
MineralsPreparations of magnesium, bromine, potassiumResumes biochemical reactions depending on the pool of these elementsProvide an adequate course of all types of metabolism

Cardiovascular group of funds

GroupRepresentativesMechanism of action
AntihypertensiveBisoprolol, Propranolol, Labetalol, CarvedilolBlockade of beta-adrenergic receptors (a decrease in the degree of influence of the peripheral nervous system on the work of the heart)
Hypertensive"Caffeine", "Dobutamine", "Dopamine", "Mezaton"Stimulation of central and peripheral receptors responsible for increasing vascular tone
Antianginal"Validol"With VSD, a complex of reflex vasodilating and calming actions is more effective - it is convenient to use in women. Standard "Nitroglycerin" is often powerless

Sedatives have a slight hypotensive effect, since during autonomic reactions the cause of high blood pressure is often the emotional state of the patient. Some adaptogens may have a hypertensive effect.

Additionally use:

  1. Hormonal agents. It is prescribed for menstrual irregularities, the onset of menopause and associated dysfunctions of the autonomic nervous system. Oral contraceptive courses are usually used:
    • single-phase (with the same estrogen content);
    • biphasic (the ratio of estrogen and progesterone changes twice per cycle);
    • three-phase (three combinations of hormones are proposed).
  2. Antioxidant drugs for VSD. They increase the resistance of cell membranes to destruction in unfavorable conditions, improving the tolerance of hypoxia. Representatives:
    • "Mexidol";
    • "Trimetazidine";
    • "Mildronat";
    • Phosphocreatine.

Children and adolescents

The cause of VSD in children is often an asthenic (weakened) state of the nervous system due to the immaturity of its structures. Therefore, medical correction of violations can only be carried out by an experienced specialist after all other preventive methods have been tried.

Drugs that mildly affect the activity of the nervous system

GroupRepresentativesMechanism of actionThe rendered effect
SedativesPreparations based on plantain and mallowNormalization of the tone of the autonomic nervous systemSoft correction of the child's psychoemotional state
AdaptogensGinseng root, Leuzea, Eleutherococcus, Rhodiola roseaActivation of functional reserves of the cerebral cortexImproving performance, memorizing new material, restorative effect, prevention of hypotonic conditions
Homeopathic"Tenoten", "Ambergris grisea", "Ignatia", "Coffea Kruda", "Stafizagria", "Opium"Not scientifically described. The importance of a complex of specific symptoms in a patient before choosing a specific drug is emphasized.Reducing anxiety, fear, preventing panic attacks

For children, drugs with a milder effect are usually prescribed. But the same groups can be used in adults. The main thing is the examination and the conclusion of the doctor on the advisability of using this or that drug.

The rating of homeopathic remedies has fallen recently, and reviews of their use are controversial. It is impossible to explain the mechanism of action of these drugs in scientific language. But since VSD symptoms often occur against a background of emotional instability, the placebo (self-hypnosis) effect may be a good option.

Vasodilator drugs: what helps?

The topic of peripheral vascular expansion is especially relevant for those who suffer from hypertensive VVD.

Preparations for vasodilation

A drugGroupMechanism of action
"Pentoxifylline"Peripheral vasodilatorsInhibition of phosphodiesterase (an enzyme that destroys cAMP, a substance that affects the state of myocytes in blood vessels)
"Cinnarizin"Calcium channel blockerRelaxation of the muscle walls of the cerebral arteries
"Vincamine", "Vinpocetine"Plant alkaloids (poisons)Adaptation of cerebral circulation to the current needs of the brain tissue in oxygen
"Bendazol"Myotropic antispasmodicRelaxes vascular muscles directly
"Papaverine"

Injections

Preparations for angiodystonia, used in the form of injections

A drugGroupWay of introductionPurpose of appointment
"Phenazepam"TranquilizersIntravenous (i / v) or intramuscular (i / m)Correction of a panic attack (removes severe anxiety, horror, relieves acute mental disorders)
"Propazin"AntipsychoticsIV (diluted with glucose) or / m (pre-mixed with novocaine)Treatment of acute emotional disorders, psychomotor agitation (inappropriate actions due to blurred consciousness)
"Atropine"M-holinoblokatorSubcutaneously, i / v, i / mBlocking the activity of the parasympathetic part of the autonomic nervous system
"Milgamma"VitaminsV / mReplenishment of deficiency of B vitamins
"Actovegin"Reparant (reducing agent), microcirculation correctorV / mCorrection of metabolism in the body and cells of the nervous system, improvement of tissue blood flow, antioxidant effect

Usually, intravenous injections have to be made with fast-acting drugs in acute conditions (for example, severe panic attacks), intramuscular administration is used in the absence of the per os option.

Conclusions

The transition to drug therapy of the VSD should be after the correction of the lifestyle and conscientious psychotherapy (perhaps the psychologist will be able to convince the patient of the insolvency of cancerophobia, and the anxiety will go away without the use of sedatives and tranquilizers).

VSD is manifested by a kaleidoscope of symptoms. They are often triggered by a state of emotional instability. Therefore, the subfebrile temperature that has arisen against the background of vegetative reactions should be treated not with antipyretic, but with sedatives.

Timely prevention will help avoid exacerbations and hospitalization in the neurology department with an uncontrolled panic attack.